Scientific programme

Conference venue                       Sir Charles Wilson Building (UofG)
Conference dinner venue          Glasgow University Union building
Ceilidh                                           Glasgow University Union building

Conference schedule

Keynote talks 45 min (40 min + 5 min questions)
Top scoring abstract talks: 20 min (15 min + 5 min questions)
Selected talks 15 min (12 min + 3 min questions)
Flash talks 5 min (3 min + 2 min questions)

Tuesday 21st May 2019

10.00 Registration open, coffee

11.00 Welcome Vignir Helgason

11.15 Keynote speaker: Kevin Ryan– The story of DRAM – autophagy, nutrient sensing and cancer.

Session 1 – Chair: Ian Ganley

12.00 Top Scoring Abstract Talk: A genome-wide CRISPRi screen for ER autophagy highlights key roles of mitochondrial metabolism and ER-resident UFMylation – Jin Rui Liang– IGI, University of California, USA

12.20 CCPG1, an ER-phagy receptor, is tumour suppressive in the pancreas – Matthew Smith– Edinburgh CRUK Centre, University of Edinburgh, UK

12.35 – 14.00 Lunch, posters and company stands

Session 2 – Chair: Noor Gammoh

14.00 Atg8 interacts with transcription factor Sequoia to control the expression of autophagy genes in DrosophilaAnne-Claire Jacomin– School of Life Sciences, University of Warwick

14.15 Development of a human neuronal cell model of Beta-propeller Protein-Associated Neurodegeneration (BPAN) as a drug screening platform – Apostolos Papandreou– University College London, UK

14.30 Flash Talks 1-5: Wenxin Zhang, Danilo Faccenda, Melanie Krause, Flavia Rosianu, Kanchan Phadwal

14.55 – 15.50 Coffee, posters and company stands

Session 3 – Chair: Michelangelo Campanella

15.50 An mTORC1-to-CDK1 switch suppresses autophagy during mitosis – Simon Cook– The Babraham Institute, Cambridge, UK

16.05 Spatiotemporal analysis of M. tuberculosis infection in human iPSDM reveals complex membrane dynamics during xenophagy evasion – Elliott M. Bernard– The Francis Crick Institute, London, UK

16.20 Human LC3/GABARAP modifies proteins as well as phospholipids – Alexander Agrotis– University College London, UK

16.35 Regulation of autophagy block by Patched 1 protein-protein interactions – Cintli Morales-Alcala– University of Leeds, UK

16.50 Wrap up/Break

18.00 Keynote speaker: Harald Stenmark– Regulation of autophagy by ESCRT proteins.

19.00 Dinner at Student Union

21.00 Ceilidh

Wednesday 22nd May 2019

9.15 Keynote speaker: Mondira Kundu– ULK/Atg1 in Autophagy and Beyond.

Session 4 – Chair: Viktor Korolchuk

10.00 Top Scoring Abstract Talk: A conserved ATG2-GABARP interaction is critical for phagophore closure – David G. McEwan– University of Dundee, UK

10.20 Unveiling the role of ARFIP2 in the trafficking of ATG9A vesicles during autophagy – Stefano De Tito– The Francis Crick Institute, London, UK

10.35 Understanding c-Met trafficking and signalling on autophagic endomembranes – Marie Nollet– Barts Cancer Institute, Queen Mary University of London, UK

10.50 – 11.45 coffee

Session 5 – Chair: Jon Lane

11.45 Mitochondrial Inner Membrane Permeabilisation Enables mtDNA Release During Apoptosis – Joel Riley– CRUK Beatson Institute, Glasgow, UK

12.00 Autophagic approaches to prevent fatty liver disease – Marina Garcia-Macia– University of Salamanca, Spain

12.15 Flash talks 6-10: Muhammed Kocak, Rachel Ulferts, Javier Hervas, Amanda Demeter, Adrian Santos-Ledo

12.40 – 13.40 Lunch, posters.

Session 6 – Chair: Stephanie Kermorgant

13.40 Is autophagy a relevant target in disease-initiating cancer stem cells? – Vignir Helgason– Wolfson Wohl Cancer Research Centre, University of Glasgow, UK

13.55 Unravelling the ULK Phosphoproteome – Thomas J. Mercer– The Francis Crick Institute, London, UK

14.10 Autophagy inhibition induces hepatocyte dedifferentiation and tumourigenesis in liver – Valentin J.A. Barthet, CRUK Beatson Institute, Glasgow, UK

14.25 Autophagy regulation of TBK1-mediated Interferon responses in cancer – Mihaela Bozic– Edinburgh CRUK Centre, UK

14.40 Poster and Best Talk prizes

15.00 Closing remarks (Vignir Helgason)