Autophagy UK Network Meeting 2023

Autophagy UK Network Meeting 2023 at University of Birmingham

Our 8th annual national meeting for researchers in the field of autophagy will be held on 19-20 June 2023 at Edgbaston Park Hotel and Conference Centre in University of Birmingham.

Organizers: Sovan Sarkar (University of Birmingham, UK), Viktor Korolchuk (Newcastle University, UK).

Keynote speakers: David Rubinsztein (University of Cambridge, UK), Ivana Bjedov (University College London, UK), Carmine Settembre (Telethon Institute of Genetics and Medicine, Italy).

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Programme

Monday, 19th June 2023

9:30 – 11:00    Registration and coffee

11:00 – 11:15  Welcome remarksSovan Sarkar and Viktor Korolchuk

11:15 – 12:00  Keynote talk David Rubinsztein (University of Cambridge, UK): Autophagy, a guardian against neurodegeneration

Session 1 – Chair: Oliver Florey

12:00 – 12:15  Nicoll Matthews (Institute of Cancer Research, UK): Utilising quantitative proteomics in combination with novel tools to profile the autophagy degradome and MAP1LC3B interactome

12:15 – 12:30  Lewis Timimi (The Francis Crick Institute, UK): Targeting the V-ATPase/ATG16L1 axis

12:30 – 12:45  Ollie Haworth (William Harvey Research Institute, UK): Loss of Aryl Hydrocarbon Receptor Interacting Protein (AIP) results in a novel paediatric metabolic disorder characterised by an inability to initiate autophagy and recycle lysosomes

12:45 – 14:15  Lunch, posters and company stands

Session 2 – Chair: Ian Ganley

14:15 – 14:30  Heather Wood (University of Birmingham, UK): Can premature senescence be alleviated in the diabetic cornea through targeting mitophagy?

14:30 – 14:45  Daniele Sarnello (Beatson Cancer Research Institute, UK): BNIP3-mediated mitophagy is required for metabolic rewiring of leukemic cells in hypoxia

14:45 – 15:00  Ioanna Ch. Georgiou (University of Liverpool, UK): Inhibitors of the ubiquitin system reveal novel regulatory mechanisms of PINK1-mediated mitophagy

15:00 – 15:20  Invited talk Ioannis Nezis (University of Warwick, UK): Selected autophagy in Drosophila  

15:20 – 16:10  Coffee, posters and company stands

Women in Autophagy (WIA) coffee break: WIA is a volunteer-run international scientific network founded in 2020 to provide educational opportunities for trainees and early-stage researchers in the field of autophagy and to serve as a leadership platform for women and other under-represented identities. Membership is free and open to all. To join and learn more visit: https://www.womeninautophagy.com/

Session 3 – Chair: Simon Wilkinson

16:10 – 16:25  Joanne E. Simpson (University of Edinburgh, UK): Autophagy regulates PDGFRA-dependent brain tumour development by modulating oncogenic signalling

16:25 – 16:40  Invited talk Marina Garcia-Macia (Universidad de Salamanca, Spain): Autophagy activation as a therapy for lysosomal storage diseases: Batten disease

16:40 – 17:00  Invited talk Noor Gammoh (University of Edinburgh, UK): A lysosomal delivery mechanism required for autophagosome degradation

17.00 – 17.30  Coffee and company stands

17:30– 18:15  Keynote talkCarmine Settembre (TIGEM, Italy): SESTRIN2 regulates ER-quality control through ER-phagy

18:30 – 20:30  Dinner and drinks

20:30 – 22:30  DJ PartyDJ Monk

Tuesday, 20th June 2023

Session 4 – Chair: Marina Garcia Macia

9:15– 10:00    Keynote talk Ivana Bjedov (University College London, UK): Delaying ageing through manipulations of autophagy and protein synthesis

10:00 – 10:15  Jennifer Niven (University of Birmingham, UK): Autophagy and senescence in adaptive immune dysregulation in obesity

10:15 – 10:30  Tetsushi Kataura (Newcastle University, UK): Autophagy promotes cell survival by maintaining NAD(H) levels

10:30 – 11:20  Coffee, posters and company stands

Session 5 – Chair: Noor Gammoh

11:20 – 11:40  Invited talk Ryan Russell (University of Ottawa, Canada): ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to evade autophagy

11:40 – 11:55  Edismauro Garcia Freitas-Filho (Universidade de São Paulo, Brazil): The Rab5c GTPase dictates the engagement of LC3-associated phagocytosis (LAP) and phagosome maturation in macrophages

11:55 – 12:10  Amelia Williams (Newcastle University, UK): Determining the impact of acute and chronic stimulation of glucose metabolism on beta-cell autophagy

12:10 – 12:30  Invited talk Simon Wilkinson (University of Edinburgh, UK): Oncogene-mediated disruption of ER-phagy triggers inflammation and pancreatic cancer

12:30 – 13:45  Lunch, posters and company stands

Session 6 – Chair: Jon Lane

13:45 – 14:00  Malgorzata Zatyka (University of Birmingham, UK): Depletion of WFS1 impairs autophagy in neuronal cell models of rare disease Wolfram syndrome

14:00 – 14:15  Shiza Shaikh (University of Bristol, UK): Autophagy modulation of glial neuroinflammatory responses in Parkinson’s Disease

14:15 – 14:30  Katie Cox (University of Bristol, UK): Manipulating autophagy activity through small molecules to protect against RPE degeneration

14:30 – 14:50  Invited talk Shouqing Luo (University of Plymouth, UK): Regulation of SQSTM1/p62 droplets-based autophagy

14:50 – 15:20  Coffee and company stands

Session 7 – Chair: Ioannis Nezis

15:20 – 15:35  Simon Schnebert (Université de Pau et des Pays de lAdour, France): Chaperone-mediated autophagy in fish: a key function in the midst of a stressful environment

15:35 – 15:50  Science art talk Hanna Salmonowicz (IMol Polish Academy of Sciences, Poland): What we know, what we remember…conveying the scientific message via SciArt

15:50 – 16:10  Sponsor talk Manos Metzakopian (Bit Bio Ltd., Cambridge, UK): Opti-ox™ – Powering a new class of consistent and scalable human cells

16:10 – 16:25  Best talk and poster prizes – Sponsored by Bit Bio Ltd., Cambridge, UK

16:25 – 16:30  Closing remarksSovan Sarkar and Viktor Korolchuk _______________________________________________________________________________________________

Registration

Registration deadline: The deadline for registration and abstract submission is 18 May 2023.

Registration link: Registration and online payment link

Registration categories: Academia registration without accommodation (£200); Academia registration with accommodation (£275); Industry registration without accommodation (£300); Industry registration with accommodation (£375).

All registration categories include food and beverages during the conference, and the dinner and DJ party on 19 June 2023. Registration with accommodation includes one night accommodation on 19 June 2023 at the conference venue in Edgbaston Park Hotel and Conference Centre. Only 66 rooms are available at the conference venue on first come first serve basis. When the accommodation at the venue reaches the maximum capacity, then only registration without accommodation will be available.

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Contact Us

For queries about the conference: Sovan Sarkar [s.sarkar@bham.ac.uk] and Viktor Korolchuk [viktor.korolchuk@newcastle.ac.uk]

For queries about the online registration payment: med-cpdbookings@contacts.bham.ac.uk

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Directions

Conference venue: Edgbaston Park Hotel and Conference Centre in University of Birmingham.

Address: 53 Edgbaston Park Road, Birmingham B15 2RS, UK.

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